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Google DeepMind Releases AlphaGenome Atlas With Precomputed Molecular Effect Predictions and AVI Scores for 9 Billion Human DNA Variants

Google DeepMind has released AlphaGenome Atlas, a catalogue of precomputed predictions for the molecular effects of every possible single-nucleotide variant in the human genome. That is roughly 9 billion single-letter changes. The release also introduces the AlphaGenome Variant Impact (AVI) score, a single number that ranks variants by predicted impact, plus per-variant feature attributions and […]

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Reducto Releases r-1: A Single Pass Document Parsing Model That Cuts Errors 20% at 1 Cent Per Page

Last week, Reducto announced r-1. It is the first model in a new parsing family built on a rewritten architecture, and it replaces the company’s multi stage agentic OCR with one full page pass. Reducto says r-1 is more accurate than its most powerful legacy agentic models, faster, and up to 6x cheaper. Is it

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OpenBMB Releases MiniCPM5-2B: A 2.52B Dense Model Averaging 53.9 Across 34 Benchmarks and Built to Run On Device

OpenBMB has released MiniCPM5-2B, the second checkpoint in the MiniCPM5 series and the follow-up to MiniCPM5-1B. It is a dense causal language model with 2,516,756,480 parameters, of which 1,981,982,720 sit outside the embeddings. It uses 42 layers, grouped-query attention with 16 query heads and 2 key/value heads, and a native context window of 131,072 tokens.

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Axis Robotics Releases AXIS: A Browser-Based Data Engine With 207 Robot Manipulation Tasks and 50,129 Trajectories

Robot manipulation datasets have grown far slower than the models trained on them, mostly because collection stays closed and centralized. Expert operators gather demonstrations on lab hardware, process them offline, and ship a fixed benchmark that never grows again. A research team from Axis Robotics, UC Berkeley, Georgia Tech, NTU… is proposing a different shape

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IFM Releases K2 Horizon: Six Apache 2.0 Models From 0.9B to 375B

Most open model launches release one checkpoint and a benchmark table. The Institute of Foundation Models (IFM) released something wider last week. IFM is the frontier lab launched by MBZUAI in May 2025. K2 Horizon is a fleet of six models: 375B-A23B, 36B-A4B, 32B, 7B, 3.7B and 0.9B. Shipping alongside them are the pre-training corpus,

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H Company Releases NeoMME: A Family of 260M and 800M Single-Tower Multimodal Encoders That Drop the Vision Tower and Causal Decoder

Most visual document retrievers in production today are hand-me-downs. ColPali and the models that followed it take a generative vision-language model and repurpose it as an encoder. The result still carries a separately pretrained vision tower and a causal decoder that never generates a token. That is parameter and compute overhead for a task that

H Company Releases NeoMME: A Family of 260M and 800M Single-Tower Multimodal Encoders That Drop the Vision Tower and Causal Decoder Read More »

UC Berkeley Researchers Release CUA-Lite, an Open Platform Unifying Sandboxes, Data, Evaluation and RL for Computer-Use Agents

A team of researchers from UC Berkeley have released CUA-Lite, an open platform for computer-use agents (CUAs). The argument behind it is infrastructural rather than model-centric: training and benchmarking a CUA requires four pieces: agents, environments, traces, and a framework to evaluate and train them and all four are currently fragmented across separate repositories with

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GitHub Introduces Project HydraFusion: Runtime Multi-Model Orchestration That Builds a Workflow Per Coding Task in Copilot CLI

GitHub has released Project HydraFusion, a research preview that stops treating model choice as a one-time setting. Instead of routing your prompt to a single model, HydraFusion builds an execution plan per request. It can draft with one model, have a second model critique the draft, or escalate to a stronger model when a quality

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Nous Research Adds One-Click Local Model Setup to Hermes Desktop

The hard part of running an open-weights model locally was never the model. It was everything before it, reading VRAM specs, guessing which quantization fits, setting context length and GPU layer counts, then finding out at load time that the file is three gigabytes too large. Nous Research has collapsed that sequence into a single

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Adaption Labs Introduces ‘Invent a Dataset’: Training Data Generated From a Task Description, Not a Seed Corpus

This week, Adaption Labs released Invent a Dataset. The feature generates a structured, training-ready dataset from a description of the behavior you want a model to learn. You do not arrive with a seed corpus, a predefined schema, or a labeling guide. Is it deployable? Yes, with one caveat. Invent a Dataset is live now

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