Proteins

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Looking beyond natural sequences

A protein’s function is determined by its structure, and structure — the way a protein folds — is determined by its sequence of amino acids, the building blocks of proteins. Many methods for designing novel proteins, including examples that could bind to a disease-causing molecule in our cells, involve a two-step process: The structure comes first, […]

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Bringing AI-driven protein-design tools to biologists everywhere

Artificial intelligence is already proving it can accelerate drug development and improve our understanding of disease. But to turn AI into novel treatments we need to get the latest, most powerful models into the hands of scientists.The problem is that most scientists aren’t machine-learning experts. Now the company OpenProtein.AI is helping scientists stay on the

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MIT engineers design proteins by their motion, not just their shape

Proteins are far more than nutrients we track on a food label. Present in every cell of our bodies, they work like nature’s molecular machines. They walk, stretch, bend, and flex to do their jobs, pumping blood, fighting disease, building tissue, and many other jobs too small for the eye to see. Their power doesn’t

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With AlphaGenome, Researchers Are Using A.I. to Decode the Human Blueprint

AlphaGenome is a leap forward in the ability to study the human blueprint. But the fine workings of our DNA are still largely a mystery.

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MIT scientists debut a generative AI model that could create molecules addressing hard-to-treat diseases

More than 300 people across academia and industry spilled into an auditorium to attend a BoltzGen seminar on Thursday, Oct. 30, hosted by the Abdul Latif Jameel Clinic for Machine Learning in Health (MIT Jameel Clinic). Headlining the event was MIT PhD student and BoltzGen’s first author Hannes Stärk, who had announced BoltzGen just a few days

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