Antibiotics

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Using synthetic biology and AI to address global antimicrobial resistance threat

James J. Collins, the Termeer Professor of Medical Engineering and Science at MIT and faculty co-lead of the Abdul Latif Jameel Clinic for Machine Learning in Health, is embarking on a multidisciplinary research project that applies synthetic biology and generative artificial intelligence to the growing global threat of antimicrobial resistance (AMR).The research project is sponsored […]

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3 Questions: Using AI to accelerate the discovery and design of therapeutic drugs

In the pursuit of solutions to complex global challenges including disease, energy demands, and climate change, scientific researchers, including at MIT, have turned to artificial intelligence, and to quantitative analysis and modeling, to design and construct engineered cells with novel properties. The engineered cells can be programmed to become new therapeutics — battling, and perhaps

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The Guardian view on antibiotics: recent breakthroughs are great news, but humanity is losing the bigger race | Editorial

Our magic bullets are increasingly rare and ineffective. The golden age of discovery is over and the way we develop and use drugs needs to changeDuring her tenure as director general of the World Health Organization, Dr Margaret Chan used to say that all of the “easy” antibiotics had already been found. Her point was that

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AI maps how a new antibiotic targets gut bacteria

For patients with inflammatory bowel disease, antibiotics can be a double-edged sword. The broad-spectrum drugs often prescribed for gut flare-ups can kill helpful microbes alongside harmful ones, sometimes worsening symptoms over time. When fighting gut inflammation, you don’t always want to bring a sledgehammer to a knife fight.Researchers at MIT’s Computer Science and Artificial Intelligence

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